Which tests are included in a Liver Function Test (LFT)?

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Liver Function Tests (LFTs) are a series of blood tests that provide information about the state of a patient's liver. The focus of these tests is primarily on enzymes and proteins that reflect the liver's synthetic and metabolic functions. The inclusion of AST (aspartate aminotransferase), ALT (alanine aminotransferase), and Alk Phos (alkaline phosphatase) is crucial because:

  • AST and ALT are enzymes that indicate hepatocellular injury; they are released into the bloodstream when liver cells are damaged. A higher level of these enzymes can signify conditions like hepatitis, liver cirrhosis, or liver injuries due to various causes.
  • Alkaline phosphatase (Alk Phos) is an enzyme that can indicate cholestasis or bile duct obstruction, as well as other liver diseases. Elevated levels can suggest biliary obstruction or liver diseases.

Together, these tests help healthcare providers assess liver health, determine the presence of liver disease, and monitor the effects of treatment or disease progression. Hence, this option embodies the essence of what constitutes a Liver Function Test, focusing on liver-specific markers.

In contrast, elements like BUN (blood urea nitrogen), creatinine, troponin,

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