What condition results in weak or fragile bones?

Osteoporosis is a condition characterized by a significant decrease in bone density and strength, leading to weak or fragile bones. This happens due to an imbalance between bone resorption and bone formation. When osteoclasts (the cells that break down bone) outpace osteoblasts (the cells that build bone), the overall result is a loss of bone mass.

The factors contributing to osteoporosis may include aging, hormonal changes (especially in postmenopausal women), nutritional deficiencies (such as lack of calcium and vitamin D), and sedentary lifestyle. As bones become more porous and brittle, individuals are at a higher risk for fractures, even with minor falls or injuries. The silent nature of the condition makes it important to identify and manage it early to prevent fractures and related complications.

Other conditions mentioned, such as rheumatoid arthritis and degenerative joint disease, primarily affect the joints and not directly the density of bones, while carcinoma involves cancerous growths that may impact bone health, but they do not specifically lead to the widespread issue of bone fragility in the same manner as osteoporosis.